Simulated microgravity inhibits L-type calcium channel currents partially by the up-regulation of miR-103 in MC3T3-E1 osteoblasts

L-type voltage-sensitive calcium channels (LTCCs), particularly Cav1.2 LTCCs, play fundamental roles in cellular responses to mechanical stimuli in osteoblasts. Numerous studies have shown that mechanical loading promotes bone formation, whereas the removal of this stimulus under microgravity condit...

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Detalles Bibliográficos
Autores principales: Sun, Zhongyang, Cao, Xinsheng, Zhang, Zhuo, Hu, Zebing, Zhang, Lianchang, Wang, Han, Zhou, Hua, Li, Dongtao, Zhang, Shu, Xie, Manjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308706/
https://www.ncbi.nlm.nih.gov/pubmed/25627864
http://dx.doi.org/10.1038/srep08077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308706/
https://www.ncbi.nlm.nih.gov/pubmed/25627864
http://dx.doi.org/10.1038/srep08077

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