Direct Enantioselective Conjugate Addition of Carboxylic Acids with Chiral Lithium Amides as Traceless Auxiliaries

[Image: see text] Michael addition is a premier synthetic method for carbon–carbon and carbon–heteroatom bond formation. Using chiral dilithium amides as traceless auxiliaries, we report the direct enantioselective Michael addition of carboxylic acids. A free carboxyl group in the product provides v...

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Detalles Bibliográficos
Autores principales: Lu, Ping, Jackson, Jeffrey J., Eickhoff, John A., Zakarian, Armen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308744/
https://www.ncbi.nlm.nih.gov/pubmed/25562717
http://dx.doi.org/10.1021/ja512213c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308744/
https://www.ncbi.nlm.nih.gov/pubmed/25562717
http://dx.doi.org/10.1021/ja512213c

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