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Temporal profiles of synaptic plasticity-related signals in adult mouse hippocampus with methotrexate treatment☆

Methotrexate, which is used to treat many malignancies and autoimmune diseases, affects brain functions including hippocampal-dependent memory function. However, the precise mechanisms underlying methotrexate-induced hippocampal dysfunction are poorly understood. To evaluate temporal changes in syna...

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Detalles Bibliográficos
Autores principales: Yang, Miyoung, Kim, Juhwan, Kim, Sung-Ho, Kim, Joong-Sun, Shin, Taekyun, Moon, Changjong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308769/
https://www.ncbi.nlm.nih.gov/pubmed/25657706
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.21.008