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Temporal profiles of synaptic plasticity-related signals in adult mouse hippocampus with methotrexate treatment☆
Methotrexate, which is used to treat many malignancies and autoimmune diseases, affects brain functions including hippocampal-dependent memory function. However, the precise mechanisms underlying methotrexate-induced hippocampal dysfunction are poorly understood. To evaluate temporal changes in syna...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308769/ https://www.ncbi.nlm.nih.gov/pubmed/25657706 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.21.008 |