In vivo production of a novel glycoconjugate vaccine against Shigella flexneri 2a in recombinant Escherichia coli: identification of stimulating factors for in vivo glycosylation

BACKGROUND: Glycoconjugated vaccines composed of polysaccharide antigens covalently linked to immunogenic carrier proteins have proved to belong to the most effective and safest vaccines for combating bacterial pathogens. The functional transfer of the N-glycosylation machinery from Campylobacter je...

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Detalles Bibliográficos
Autores principales: Kämpf, Michael M, Braun, Martin, Sirena, Dominique, Ihssen, Julian, Thöny-Meyer, Linda, Ren, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308876/
https://www.ncbi.nlm.nih.gov/pubmed/25612741
http://dx.doi.org/10.1186/s12934-015-0195-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308876/
https://www.ncbi.nlm.nih.gov/pubmed/25612741
http://dx.doi.org/10.1186/s12934-015-0195-7

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