T cell-NF-κB activation is required for tumor control in vivo

BACKGROUND: T cells have the capacity to eliminate tumors but the signaling pathways by which they do so are incompletely understood. T cell priming requires activation of the transcription factors AP-1, NFAT and NF-κB downstream of the TCR, but whether activation of T cell-NF-κB in vivo is required...

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Detalles Bibliográficos
Autores principales: Barnes, Sarah E, Wang, Ying, Chen, Luqiu, Molinero, Luciana L, Gajewski, Thomas F, Evaristo, Cesar, Alegre, Maria-Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308877/
https://www.ncbi.nlm.nih.gov/pubmed/25648675
http://dx.doi.org/10.1186/s40425-014-0045-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308877/
https://www.ncbi.nlm.nih.gov/pubmed/25648675
http://dx.doi.org/10.1186/s40425-014-0045-x

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