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Expression profile and down-regulation of argininosuccinate synthetase in hepatocellular carcinoma in a transgenic mouse model

BACKGROUND: Argininosuccinate synthetase (ASS) participates in urea and nitric oxide production and is a rate-limiting enzyme in arginine biosynthesis. Regulation of ASS expression appears complex and dynamic. In addition to transcriptional regulation, a novel post-transcriptional regulation affecti...

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Detalles Bibliográficos
Autores principales: Shiue, Shih-Chang, Huang, Miao-Zeng, Tsai, Ting-Fen, Chang, Alice Chien, Choo, Kong Bung, Huang, Chiu-Jung, Su, Tsung-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308890/
https://www.ncbi.nlm.nih.gov/pubmed/25616743
http://dx.doi.org/10.1186/s12929-015-0114-6