Interleukin-1β regulates the expression of glucocorticoid receptor isoforms in nasal polyps in vitro via p38 MAPK and JNK signal transduction pathways

BACKGROUND: To explore the upstream signal transduction mechanisms responsible for the imbalanced expression of glucocorticoid receptor (GR) isoforms in chronic rhinosinusitis (CRS) mucosa. METHODS: An in vitro model of Glucocorticoid resistance was established by inducing nasal polyp tissue with IL...

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Detalles Bibliográficos
Autores principales: Wang, Zhenlin, Li, Peng, Zhang, Qiuhang, Lv, Haili, Liu, Junqi, Si, Jinyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308899/
https://www.ncbi.nlm.nih.gov/pubmed/25632272
http://dx.doi.org/10.1186/s12950-014-0046-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308899/
https://www.ncbi.nlm.nih.gov/pubmed/25632272
http://dx.doi.org/10.1186/s12950-014-0046-z

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