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Interleukin-1β regulates the expression of glucocorticoid receptor isoforms in nasal polyps in vitro via p38 MAPK and JNK signal transduction pathways

BACKGROUND: To explore the upstream signal transduction mechanisms responsible for the imbalanced expression of glucocorticoid receptor (GR) isoforms in chronic rhinosinusitis (CRS) mucosa. METHODS: An in vitro model of Glucocorticoid resistance was established by inducing nasal polyp tissue with IL...

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Detalles Bibliográficos
Autores principales:	Wang, Zhenlin, Li, Peng, Zhang, Qiuhang, Lv, Haili, Liu, Junqi, Si, Jinyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308899/ https://www.ncbi.nlm.nih.gov/pubmed/25632272 http://dx.doi.org/10.1186/s12950-014-0046-z

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