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Comprehensive miRNA sequence analysis reveals survival differences in diffuse large B-cell lymphoma patients

BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) is an aggressive disease, with 30% to 40% of patients failing to be cured with available primary therapy. microRNAs (miRNAs) are RNA molecules that attenuate expression of their mRNA targets. To characterize the DLBCL miRNome, we sequenced miRNAs fro...

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Detalles Bibliográficos
Autores principales: Lim, Emilia L, Trinh, Diane L, Scott, David W, Chu, Andy, Krzywinski, Martin, Zhao, Yongjun, Robertson, A Gordon, Mungall, Andrew J, Schein, Jacqueline, Boyle, Merrill, Mottok, Anja, Ennishi, Daisuke, Johnson, Nathalie A, Steidl, Christian, Connors, Joseph M, Morin, Ryan D, Gascoyne, Randy D, Marra, Marco A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308918/
https://www.ncbi.nlm.nih.gov/pubmed/25723320
http://dx.doi.org/10.1186/s13059-014-0568-y