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Synthesis, HIV-1 RT inhibitory, antibacterial, antifungal and binding mode studies of some novel N-substituted 5-benzylidine-2,4-thiazolidinediones

BACKGROUND: Structural modifications of thiazolidinediones at 3(rd) and 5(th) position have exhibited significant biological activities. In view of the facts, and based on in silico studies carried out on thiazolidine-2,4-diones as HIV-1- RT inhibitors, a novel series of 2,4-thiazolidinedione analog...

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Detalles Bibliográficos
Autores principales: Bahare, Radhe Shyam, Ganguly, Swastika, Choowongkomon, Kiattawee, Seetaha, Supaporn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308940/
https://www.ncbi.nlm.nih.gov/pubmed/25617150
http://dx.doi.org/10.1186/s40199-014-0086-1