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Vascular calcification is dependent on plasma levels of pyrophosphate

Plasma levels of pyrophosphate, an endogenous inhibitor of vascular calcification, are reduced in end-stage renal disease and correlate inversely with arterial calcification. However, it is not known whether the low plasma levels are directly pathogenic or are merely a marker of reduced tissue level...

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Detalles Bibliográficos
Autores principales: Lomashvili, Koba A., Narisawa, Sonoko, Millán, Jose Luis, O’Neill, W. Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308968/
https://www.ncbi.nlm.nih.gov/pubmed/24717293
http://dx.doi.org/10.1038/ki.2013.521