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Apolipoprotein E Mimetic Promotes Functional and Histological Recovery in Lysolecithin-Induced Spinal Cord Demyelination in Mice

OBJECTIVE: Considering demyelination is the pathological hallmark of multiple sclerosis (MS), reducing demyelination and/or promoting remyelination is a practical therapeutic strategy to improve functional recovery for MS. An apolipoprotein E (apoE)-mimetic peptide COG112 has previously demonstrated...

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Detalles Bibliográficos
Autores principales: Gu, Zhen, Li, Fengqiao, Zhang, Yi Ping, Shields, Lisa B.E., Hu, Xiaoling, Zheng, Yiyan, Yu, Panpan, Zhang, Yongjie, Cai, Jun, Vitek, Michael P., Shields, Christopher B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309015/
https://www.ncbi.nlm.nih.gov/pubmed/25642353
http://dx.doi.org/10.4172/2155-9562.S12-010