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Mechanistic Insights into a Classic Wonder Drug—Aspirin
[Image: see text] Aspirin, one of the oldest and most common anti-inflammatory agents, has recently been shown to reduce cancer risks. The principal pharmacological effects of aspirin are known to arise from its covalent modification of cyclooxygenase-2 (COX-2) through acetylation of Ser530, but the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309031/ https://www.ncbi.nlm.nih.gov/pubmed/25514511 http://dx.doi.org/10.1021/ja5112964 |