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Cardiac Magnetic Resonance Assessment of Interstitial Myocardial Fibrosis and Cardiomyocyte Hypertrophy in Hypertensive Mice Treated With Spironolactone

BACKGROUND: Nearly 50% of patients with heart failure (HF) have preserved LV ejection fraction, with interstitial fibrosis and cardiomyocyte hypertrophy as early manifestations of pressure overload. However, methods to assess both tissue characteristics dynamically and noninvasively with therapy are...

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Detalles Bibliográficos
Autores principales: Coelho‐Filho, Otavio R., Shah, Ravi V., Neilan, Tomas G., Mitchell, Richard, Moreno, Heitor, Kwong, Raymond, Jerosch‐Herold, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309062/
https://www.ncbi.nlm.nih.gov/pubmed/24965024
http://dx.doi.org/10.1161/JAHA.114.000790