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Functional Analysis of the TRIB1 Associated Locus Linked to Plasma Triglycerides and Coronary Artery Disease

BACKGROUND: The TRIB1 locus has been linked to hepatic triglyceride metabolism in mice and to plasma triglycerides and coronary artery disease in humans. The lipid‐associated single nucleotide polymorphisms (SNPs), identified by genome‐wide association studies, are located ≈30 kb downstream from TRI...

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Detalles Bibliográficos
Autores principales: Douvris, Adrianna, Soubeyrand, Sébastien, Naing, Thet, Martinuk, Amy, Nikpay, Majid, Williams, Andrew, Buick, Julie, Yauk, Carole, McPherson, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309087/
https://www.ncbi.nlm.nih.gov/pubmed/24895164
http://dx.doi.org/10.1161/JAHA.114.000884