Different Degrees of NADPH Oxidase 2 Regulation and In Vivo Platelet Activation: Lesson From Chronic Granulomatous Disease

BACKGROUND: In vitro study showed that NADPH oxidase (NOx), the most important enzyme producing reactive oxygen species (ROS), plays a role in the process of platelet activation. However, it is unclear if changes in its activity affect platelet activation in vivo. METHODS AND RESULTS: In vivo and ex...

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Detalles Bibliográficos
Autores principales: Carnevale, Roberto, Loffredo, Lorenzo, Sanguigni, Valerio, Plebani, Alessandro, Rossi, Paolo, Pignata, Claudio, Martire, Baldassarre, Finocchi, Andrea, Pietrogrande, Maria Cristina, Azzari, Chiara, Soresina, Anna Rosa, Martino, Silvana, Cirillo, Emilia, Martino, Francesco, Pignatelli, Pasquale, Violi, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309093/
https://www.ncbi.nlm.nih.gov/pubmed/24973227
http://dx.doi.org/10.1161/JAHA.114.000920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309093/
https://www.ncbi.nlm.nih.gov/pubmed/24973227
http://dx.doi.org/10.1161/JAHA.114.000920

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