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Arrhythmogenic Calmodulin Mutations Disrupt Intracellular Cardiomyocyte Ca(2+) Regulation by Distinct Mechanisms
BACKGROUND: Calmodulin (CaM) mutations have been identified recently in subjects with congenital long QT syndrome (LQTS) or catecholaminergic polymorphic ventricular tachycardia (CPVT), but the mechanisms responsible for these divergent arrhythmia‐susceptibility syndromes in this context are unknown...
Autores principales: | Yin, Guo, Hassan, Faisal, Haroun, Ayman R., Murphy, Lisa L., Crotti, Lia, Schwartz, Peter J., George, Alfred L., Satin, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309107/ https://www.ncbi.nlm.nih.gov/pubmed/24958779 http://dx.doi.org/10.1161/JAHA.114.000996 |
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