The Potential of panHER Inhibition in Cancer

Purpose: Hyper-activation of the HER (erbB) family receptors, HER 1-4, leads to up-regulation of the three vital signaling pathways: mitogen activated protein kinase, phosphoinositide 3-kinase/AKT, and Janus kinase/signal transducer and activator of transcription pathways. Blocking HER1/EGFR has a l...

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Detalles Bibliográficos
Autores principales: Wang, Xiaochun, Batty, Kathleen M., Crowe, Philip J., Goldstein, David, Yang, Jia-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309158/
https://www.ncbi.nlm.nih.gov/pubmed/25674538
http://dx.doi.org/10.3389/fonc.2015.00002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309158/
https://www.ncbi.nlm.nih.gov/pubmed/25674538
http://dx.doi.org/10.3389/fonc.2015.00002

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