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Minocycline treatment ameliorates interferon-alpha- induced neurogenic defects and depression-like behaviors in mice

Interferon-alpha (IFN-α) is a proinflammatory cytokine that is widely used for the treatment of chronic viral hepatitis and malignancy, because of its immune-activating, antiviral, and antiproliferative properties. However, long-term IFN-α treatment frequently causes depression, which limits its cli...

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Detalles Bibliográficos
Autores principales: Zheng, Lian-Shun, Kaneko, Naoko, Sawamoto, Kazunobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309184/
https://www.ncbi.nlm.nih.gov/pubmed/25674053
http://dx.doi.org/10.3389/fncel.2015.00005