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Sesquiterpene Lactones Inhibit Advanced Oxidation Protein Product-Induced MCP-1 Expression in Podocytes via an IKK/NF-κB-Dependent Mechanism

Inflammation is a relevant factor in the pathogenesis of diabetes nephropathy (DN). Sesquiterpene lactones (SLs), originally isolated from Tanacetum parthenium, have been reported to exhibit anti-inflammatory effects but few studies have examined their effects on DN. To determine whether advanced ox...

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Detalles Bibliográficos
Autores principales: Zhao, Yan, Chen, Si-jia, Wang, Jian-cheng, Niu, Hong-xin, Jia, Qian-qian, Chen, Xiao-wen, Du, Xiao-yan, Lu, Lu, Huang, Bo, Zhang, Quan, Chen, Yue, Long, Hai-bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309307/
https://www.ncbi.nlm.nih.gov/pubmed/25664142
http://dx.doi.org/10.1155/2015/934058