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RNA export factor Ddx19 is required for nuclear import of the SRF coactivator MKL1

Controlled transport of macromolecules between the cytoplasm and nucleus is essential for homeostatic regulation of cellular functions. For instance, gene expression entails coordinated nuclear import of transcriptional regulators to activate transcription and nuclear export of the resulting messeng...

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Detalles Bibliográficos
Autores principales: Rajakylä, Eeva Kaisa, Viita, Tiina, Kyheröinen, Salla, Huet, Guillaume, Treisman, Richard, Vartiainen, Maria K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309436/
https://www.ncbi.nlm.nih.gov/pubmed/25585691
http://dx.doi.org/10.1038/ncomms6978