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A CD8 T Cell/Indoleamine 2,3-Dioxygenase Axis Is Required for Mesenchymal Stem Cell Suppression of Human Systemic Lupus Erythematosus

OBJECTIVE: Allogeneic mesenchymal stem cells (MSCs) exhibit therapeutic effects in human autoimmune diseases such as systemic lupus erythematosus (SLE), but the underlying mechanisms remain largely unknown. The aim of this study was to investigate how allogeneic MSCs mediate immunosuppression in lup...

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Detalles Bibliográficos
Autores principales: Wang, Dandan, Feng, Xuebing, Lu, Lin, Konkel, Joanne E, Zhang, Huayong, Chen, Zhiyong, Li, Xia, Gao, Xiang, Lu, Liwei, Shi, Songtao, Chen, Wanjun, Sun, Lingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309486/
https://www.ncbi.nlm.nih.gov/pubmed/24756936
http://dx.doi.org/10.1002/art.38674