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Novel, high incidence exercise-induced muscle bleeding model in hemophilia B mice: rationale, development and prophylactic intervention

INTRODUCTION: Muscle hematomas are the second most common complication of hemophilia and insufficient treatment may result in serious and even life-threatening complications. Hemophilic dogs and rats do experience spontaneous muscle bleeding, but currently, no experimental animal model is available...

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Detalles Bibliográficos
Autores principales: Tranholm, M, Kristensen, A T, Broberg, M L, Groth, M P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309488/
https://www.ncbi.nlm.nih.gov/pubmed/25370152
http://dx.doi.org/10.1111/jth.12775