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The Mutational Landscape in Pediatric Acute Lymphoblastic Leukemia Deciphered by Whole Genome Sequencing

Genomic characterization of pediatric acute lymphoblastic leukemia (ALL) has identified distinct patterns of genes and pathways altered in patients with well-defined genetic aberrations. To extend the spectrum of known somatic variants in ALL, we performed whole genome and transcriptome sequencing o...

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Detalles Bibliográficos
Autores principales: Lindqvist, Carl Mårten, Nordlund, Jessica, Ekman, Diana, Johansson, Anna, Moghadam, Behrooz Torabi, Raine, Amanda, Övernäs, Elin, Dahlberg, Johan, Wahlberg, Per, Henriksson, Niklas, Abrahamsson, Jonas, Frost, Britt-Marie, Grandér, Dan, Heyman, Mats, Larsson, Rolf, Palle, Josefine, Söderhäll, Stefan, Forestier, Erik, Lönnerholm, Gudmar, Syvänen, Ann-Christine, Berglund, Eva C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309499/
https://www.ncbi.nlm.nih.gov/pubmed/25355294
http://dx.doi.org/10.1002/humu.22719