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Strategies of Eradicating Glioma Cells: A Multi-Scale Mathematical Model with MiR-451-AMPK-mTOR Control

The cellular dispersion and therapeutic control of glioblastoma, the most aggressive type of primary brain cancer, depends critically on the migration patterns after surgery and intracellular responses of the individual cancer cells in response to external biochemical and biomechanical cues in the m...

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Detalles Bibliográficos
Autores principales: Kim, Yangjin, Powathil, Gibin, Kang, Hyunji, Trucu, Dumitru, Kim, Hyeongi, Lawler, Sean, Chaplain, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309536/
https://www.ncbi.nlm.nih.gov/pubmed/25629604
http://dx.doi.org/10.1371/journal.pone.0114370