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Strategies of Eradicating Glioma Cells: A Multi-Scale Mathematical Model with MiR-451-AMPK-mTOR Control
The cellular dispersion and therapeutic control of glioblastoma, the most aggressive type of primary brain cancer, depends critically on the migration patterns after surgery and intracellular responses of the individual cancer cells in response to external biochemical and biomechanical cues in the m...
Autores principales: | Kim, Yangjin, Powathil, Gibin, Kang, Hyunji, Trucu, Dumitru, Kim, Hyeongi, Lawler, Sean, Chaplain, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309536/ https://www.ncbi.nlm.nih.gov/pubmed/25629604 http://dx.doi.org/10.1371/journal.pone.0114370 |
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