Inhibition of G-Protein βγ Signaling Enhances T Cell Receptor-Stimulated Interleukin 2 Transcription in CD4(+) T Helper Cells

G-protein-coupled receptor (GPCR) signaling modulates the expression of cytokines that are drug targets for immune disorders. However, although GPCRs are common targets for other diseases, there are few GPCR-based pharmaceuticals for inflammation. The purpose of this study was to determine whether t...

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Detalles Bibliográficos
Autores principales: Yost, Evan A., Hynes, Thomas R., Hartle, Cassandra M., Ott, Braden J., Berlot, Catherine H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309538/
https://www.ncbi.nlm.nih.gov/pubmed/25629163
http://dx.doi.org/10.1371/journal.pone.0116575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309538/
https://www.ncbi.nlm.nih.gov/pubmed/25629163
http://dx.doi.org/10.1371/journal.pone.0116575

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