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Conservation and Immunogenicity of Novel Antigens in Diverse Isolates of Enterotoxigenic Escherichia coli

BACKGROUND: Enterotoxigenic Escherichia coli (ETEC) are common causes of diarrheal morbidity and mortality in developing countries for which there is currently no vaccine. Heterogeneity in classical ETEC antigens known as colonization factors (CFs) and poor efficacy of toxoid-based approaches to dat...

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Detalles Bibliográficos
Autores principales: Luo, Qingwei, Qadri, Firdausi, Kansal, Rita, Rasko, David A., Sheikh, Alaullah, Fleckenstein, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309559/
https://www.ncbi.nlm.nih.gov/pubmed/25629897
http://dx.doi.org/10.1371/journal.pntd.0003446