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Genetic Variants Modulating CRIPTO Serum Levels Identified by Genome-Wide Association Study in Cilento Isolates

Cripto, the founding member of the EGF-CFC genes, plays an essential role in embryo development and is involved in cancer progression. Cripto is a GPI-anchored protein that can interact with various components of multiple signaling pathways, such as TGF-β, Wnt and MAPK, driving different processes,...

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Detalles Bibliográficos
Autores principales: Ruggiero, Daniela, Nappo, Stefania, Nutile, Teresa, Sorice, Rossella, Talotta, Francesco, Giorgio, Emilia, Bellenguez, Celine, Leutenegger, Anne-Louise, Liguori, Giovanna L., Ciullo, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309561/
https://www.ncbi.nlm.nih.gov/pubmed/25629528
http://dx.doi.org/10.1371/journal.pgen.1004976