Rapid Screening of Gene Function by Systemic Delivery of Morpholino Oligonucleotides to Live Mouse Embryos

Traditional gene targeting methods in mice are complex and time consuming, especially when conditional deletion methods are required. Here, we describe a novel technique for assessing gene function by injection of modified antisense morpholino oligonucleotides (MOs) into the heart of mid-gestation m...

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Detalles Bibliográficos
Autores principales: McClelland, Kathryn S., Wainwright, Elanor N., Bowles, Josephine, Koopman, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309589/
https://www.ncbi.nlm.nih.gov/pubmed/25629157
http://dx.doi.org/10.1371/journal.pone.0114932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309589/
https://www.ncbi.nlm.nih.gov/pubmed/25629157
http://dx.doi.org/10.1371/journal.pone.0114932

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