Systemic and Cerebral Iron Homeostasis in Ferritin Knock-Out Mice

Ferritin, a 24-mer heteropolymer of heavy (H) and light (L) subunits, is the main cellular iron storage protein and plays a pivotal role in iron homeostasis by modulating free iron levels thus reducing radical-mediated damage. The H subunit has ferroxidase activity (converting Fe(II) to Fe(III)), wh...

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Detalles Bibliográficos
Autores principales: Li, Wei, Garringer, Holly J., Goodwin, Charles B., Richine, Briana, Acton, Anthony, VanDuyn, Natalia, Muhoberac, Barry B., Irimia-Dominguez, Jose, Chan, Rebecca J., Peacock, Munro, Nass, Richard, Ghetti, Bernardino, Vidal, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309591/
https://www.ncbi.nlm.nih.gov/pubmed/25629408
http://dx.doi.org/10.1371/journal.pone.0117435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309591/
https://www.ncbi.nlm.nih.gov/pubmed/25629408
http://dx.doi.org/10.1371/journal.pone.0117435

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