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Low Prevalence of CHEK2 Gene Mutations in Multiethnic Cohorts of Breast Cancer Patients in Malaysia

CHEK2 is a protein kinase that is involved in cell-cycle checkpoint control after DNA damage. Germline mutations in CHEK2 gene have been associated with increase in breast cancer risk. The aim of this study is to identify the CHEK2 gene germline mutations among high-risk breast cancer patients and i...

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Detalles Bibliográficos
Autores principales: Mohamad, Suriati, Isa, Nurismah Md, Muhammad, Rohaizak, Emran, Nor Aina, Kitan, Nor Mayah, Kang, Peter, Kang, In Nee, Taib, Nur Aishah Mohd, Teo, Soo Hwang, Akmal, Sharifah Noor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309602/
https://www.ncbi.nlm.nih.gov/pubmed/25629968
http://dx.doi.org/10.1371/journal.pone.0117104