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Low Prevalence of CHEK2 Gene Mutations in Multiethnic Cohorts of Breast Cancer Patients in Malaysia
CHEK2 is a protein kinase that is involved in cell-cycle checkpoint control after DNA damage. Germline mutations in CHEK2 gene have been associated with increase in breast cancer risk. The aim of this study is to identify the CHEK2 gene germline mutations among high-risk breast cancer patients and i...
Autores principales: | Mohamad, Suriati, Isa, Nurismah Md, Muhammad, Rohaizak, Emran, Nor Aina, Kitan, Nor Mayah, Kang, Peter, Kang, In Nee, Taib, Nur Aishah Mohd, Teo, Soo Hwang, Akmal, Sharifah Noor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309602/ https://www.ncbi.nlm.nih.gov/pubmed/25629968 http://dx.doi.org/10.1371/journal.pone.0117104 |
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