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The M3 Muscarinic Receptor Is Required for Optimal Adaptive Immunity to Helminth and Bacterial Infection

Innate immunity is regulated by cholinergic signalling through nicotinic acetylcholine receptors. We show here that signalling through the M3 muscarinic acetylcholine receptor (M3R) plays an important role in adaptive immunity to both Nippostrongylus brasiliensis and Salmonella enterica serovar Typh...

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Detalles Bibliográficos
Autores principales: Darby, Matthew, Schnoeller, Corinna, Vira, Alykhan, Culley, Fiona, Bobat, Saeeda, Logan, Erin, Kirstein, Frank, Wess, Jürgen, Cunningham, Adam F., Brombacher, Frank, Selkirk, Murray E., Horsnell, William G. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309615/
https://www.ncbi.nlm.nih.gov/pubmed/25629518
http://dx.doi.org/10.1371/journal.ppat.1004636