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Key drivers of biomedical innovation in cancer drug discovery

Discovery and translational research has led to the identification of a series of “cancer drivers”—genes that, when mutated or otherwise misregulated, can drive malignancy. An increasing number of drugs that directly target such drivers have demonstrated activity in clinical trials and are shaping a...

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Detalles Bibliográficos
Autores principales: Huber, Margit A, Kraut, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309664/
https://www.ncbi.nlm.nih.gov/pubmed/25422355
http://dx.doi.org/10.15252/emmm.201404596