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Therapeutic Efficacy of Valproic Acid in a Combined Monocrotaline and Chronic Hypoxia Rat Model of Severe Pulmonary Hypertension

BACKGROUND: Pulmonary hypertension (PH) is a serious disease with poor prognosis. Reports show that cells in remodeled pulmonary arteries of PH patients have similar characteristics to cancer cells, such as exuberant inflammation, increased proliferation, and decreased apoptosis. An ideal strategy f...

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Detalles Bibliográficos
Autores principales: Lan, Beidi, Hayama, Emiko, Kawaguchi, Nanako, Furutani, Yoshiyuki, Nakanishi, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309681/
https://www.ncbi.nlm.nih.gov/pubmed/25629315
http://dx.doi.org/10.1371/journal.pone.0117211