Heparanase mediates a novel mechanism in lapatinib-resistant brain metastatic breast cancer()()

Heparanase (HPSE) is the dominant mammalian endoglycosidase and important tumorigenic, angiogenic, and pro-metastatic molecule. Highest levels of HPSE activity have been consistently detected in cells possessing highest propensities to colonize the brain, emphasizing the therapeutic potential for ta...

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Detalles Bibliográficos
Autores principales: Zhang, Lixin, Ngo, Jason A., Wetzel, Michael D., Marchetti, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309682/
https://www.ncbi.nlm.nih.gov/pubmed/25622903
http://dx.doi.org/10.1016/j.neo.2014.11.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309682/
https://www.ncbi.nlm.nih.gov/pubmed/25622903
http://dx.doi.org/10.1016/j.neo.2014.11.007

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