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RhoC Mediates Epidermal Growth Factor-Stimulated Migration and Invasion in Head and Neck Squamous Cell Carcinoma

Epidermal growth factor receptor (EGFR) is overexpressed in head and neck squamous cell carcinoma (HNSCC) where it has been shown to promote tumor cell invasion upon phosphorylation. One mechanism by which EGFR promotes tumor progression is by activating signal cascades that lead to loss of E-cadher...

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Detalles Bibliográficos
Autores principales: Tumur, Zohra, Katebzadeh, Shahbaz, Guerra, Carlos, Bhushan, Lokesh, Alkam, Tursun, Henson, Bradley S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309735/
https://www.ncbi.nlm.nih.gov/pubmed/25622907
http://dx.doi.org/10.1016/j.neo.2014.12.002