Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos

The use of TALEN and CRISPR/CAS nucleases is becoming increasingly popular as a means to edit single target sites in one-cell mouse embryos. Nevertheless, an area that has received less attention concerns the engineering of structural genome variants and the necessary religation of two distant doubl...

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Detalles Bibliográficos
Autores principales: Brandl, Christina, Ortiz, Oskar, Röttig, Bernhard, Wefers, Benedikt, Wurst, Wolfgang, Kühn, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309836/
https://www.ncbi.nlm.nih.gov/pubmed/25685662
http://dx.doi.org/10.1016/j.fob.2014.11.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309836/
https://www.ncbi.nlm.nih.gov/pubmed/25685662
http://dx.doi.org/10.1016/j.fob.2014.11.009

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