Diffuse binding of Zn(2+) to the denatured ensemble of Cu/Zn superoxide dismutase 1

The stability and structural properties of the metalloprotein superoxide dismutase 1 (SOD1) are found to depend critically on metal ions. Native SOD1 monomers coordinate one structural Zn(2+) and one redox-active Cu(2+/1+) to the active site. To do this, the Zn(2+) ions need to interact with the SOD...

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Detalles Bibliográficos
Autores principales: Szpryngiel, Scarlett, Oliveberg, Mikael, Mäler, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309841/
https://www.ncbi.nlm.nih.gov/pubmed/25685664
http://dx.doi.org/10.1016/j.fob.2014.12.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309841/
https://www.ncbi.nlm.nih.gov/pubmed/25685664
http://dx.doi.org/10.1016/j.fob.2014.12.003

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