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Telomerase activated thymidine analogue pro-drug is a new molecule targeting hepatocellular carcinoma

BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. Although hepatectomy and transplantation have significantly improved survival, there is no effective chemotherapeutic treatment for HCC and its prognosis remains poor. Sustained activation of telo...

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Detalles Bibliográficos
Autores principales: Tarocchi, Mirko, Polvani, Simone, Peired, Anna Julie, Marroncini, Giada, Calamante, Massimo, Ceni, Elisabetta, Rhodes, Daniela, Mello, Tommaso, Pieraccini, Giuseppe, Quattrone, Alessandro, Luchinat, Claudio, Galli, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309885/
https://www.ncbi.nlm.nih.gov/pubmed/24862448
http://dx.doi.org/10.1016/j.jhep.2014.05.027