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Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases

The development of in vitro amplification systems allows detecting femtomolar amounts of prion protein scrapie (PrP(Sc)) in human cerebrospinal fluid (CSF). We performed a CSF study to determine the effects of prion disease type, codon 129 genotype, PrP(Sc) type, and other disease-related factors on...

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Detalles Bibliográficos
Autores principales: Cramm, Maria, Schmitz, Matthias, Karch, André, Zafar, Saima, Varges, Daniela, Mitrova, Eva, Schroeder, Bjoern, Raeber, Alex, Kuhn, Franziska, Zerr, Inga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309904/
https://www.ncbi.nlm.nih.gov/pubmed/24809690
http://dx.doi.org/10.1007/s12035-014-8709-6