Adenovirus serotype 5 E1A expressing tumor cells elicit a tumor-specific CD8+ T cell response independent of NKG2D

The expression of the Adenovirus serotype 2 or serotype 5 (Ad2/5) E1A gene in tumor cells upregulates ligands that are recognized by the NKG2D activating receptor, which is expressed on NK cells and T cells, and reduces their tumorigenicity, a process dependent on NK cells and T cells. In some model...

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Detalles Bibliográficos
Autores principales: Korrer, Michael J., Routes, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309920/
https://www.ncbi.nlm.nih.gov/pubmed/25685658
http://dx.doi.org/10.1016/j.rinim.2015.01.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309920/
https://www.ncbi.nlm.nih.gov/pubmed/25685658
http://dx.doi.org/10.1016/j.rinim.2015.01.001

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