Serotonin Deficiency Exacerbates Acetaminophen-Induced Liver Toxicity In Mice

Acetaminophen (APAP) overdose is a major cause of acute liver failure. Peripheral 5-hydroxytryptamine (serotonin, 5-HT) is a cytoprotective neurotransmitter which is also involved in the hepatic physiological and pathological process. This study seeks to investigate the mechanisms involved in APAP-i...

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Detalles Bibliográficos
Autores principales: Zhang, Jingyao, Song, Sidong, Pang, Qing, Zhang, Ruiyao, Zhou, Lei, Liu, Sushun, Meng, Fandi, Wu, Qifei, Liu, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309973/
https://www.ncbi.nlm.nih.gov/pubmed/25631548
http://dx.doi.org/10.1038/srep08098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309973/
https://www.ncbi.nlm.nih.gov/pubmed/25631548
http://dx.doi.org/10.1038/srep08098

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