Cargando…

Serotonin Deficiency Exacerbates Acetaminophen-Induced Liver Toxicity In Mice

Acetaminophen (APAP) overdose is a major cause of acute liver failure. Peripheral 5-hydroxytryptamine (serotonin, 5-HT) is a cytoprotective neurotransmitter which is also involved in the hepatic physiological and pathological process. This study seeks to investigate the mechanisms involved in APAP-i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Jingyao, Song, Sidong, Pang, Qing, Zhang, Ruiyao, Zhou, Lei, Liu, Sushun, Meng, Fandi, Wu, Qifei, Liu, Chang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309973/ https://www.ncbi.nlm.nih.gov/pubmed/25631548 http://dx.doi.org/10.1038/srep08098

Ejemplares similares

Corrigendum: Serotonin Deficiency Exacerbates Acetaminophen-Induced Liver Toxicity In Mice
por: Zhang, Jingyao, et al.
Publicado: (2015)

5-HT Drives Mortality in Sepsis Induced by Cecal Ligation and Puncture in Mice
por: Zhang, Jingyao, et al.
Publicado: (2017)

Effects and related mechanisms of serotonin on malignant biological behavior of hepatocellular carcinoma via regulation of Yap
por: Liu, Sushun, et al.
Publicado: (2017)

Preoperative Serum and Intra-platelet Serotonin in Prognosis: Useful or Useless?
por: Yang, Qinling, et al.
Publicado: (2018)

Hepatoprotective Effect of Metadoxine on Acetaminophen-induced Liver Toxicity in Mice
por: Mazraati, Parvin, et al.
Publicado: (2018)

Hepatoprotective Effect of Citral on Acetaminophen-Induced Liver Toxicity in Mice
por: Uchida, Nancy Sayuri, et al.
Publicado: (2017)

Chlorella sp. Protective Effect on Acetaminophen-Induced Liver Toxicity in ICR Mice
por: Wu, Jia-Ping
Publicado: (2020)

Deficiency of Interleukin-15 Enhances Susceptibility to Acetaminophen-Induced Liver Injury in Mice
por: Hou, Hsein-San, et al.
Publicado: (2012)

The Role of Serotonin in Concanavalin A-Induced Liver Injury in Mice
por: Pang, Qing, et al.
Publicado: (2020)

Cathelicidin promotes liver repair after acetaminophen-induced liver injury in mice
por: Zhai, Tingting, et al.
Publicado: (2023)

Prolonged oxidative stress and delayed tissue repair exacerbate acetaminophen-induced liver injury in aged mice
por: Tanimizu, Naoki, et al.
Publicado: (2020)

Exogenous exosomes from mice with acetaminophen-induced liver injury promote toxicity in the recipient hepatocytes and mice
por: Cho, Young-Eun, et al.
Publicado: (2018)

Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice
por: Wang, Hua, et al.
Publicado: (2019)

Montelukast Prevents Mice Against Acetaminophen-Induced Liver Injury
por: Pu, Shiyun, et al.
Publicado: (2019)

Alterations in circadian rhythms aggravate Acetaminophen-induced liver injury in mice by influencing Acetaminophen metabolization and increasing intestinal permeability
por: Zhang, Kun, et al.
Publicado: (2022)

Peripheral serotonin regulates postoperative intra-abdominal adhesion formation in mice
por: Bi, Jianbin, et al.
Publicado: (2017)

Acetaminophen-induced reduction of NIMA-related kinase 7 expression exacerbates acute liver injury
por: Sun, Zhenzhen, et al.
Publicado: (2022)

The effect of acetaminophen nanoparticles on liver toxicity in a rat model
por: Biazar, Esmaeil, et al.
Publicado: (2010)

Identification of Identical Transcript Changes in Liver and Whole Blood during Acetaminophen Toxicity
por: Zhang, Liwen, et al.
Publicado: (2012)

Ringer's lactate improves liver recovery in a murine model of acetaminophen toxicity
por: Yang, Runkuan, et al.
Publicado: (2011)

Plasma exosomes exacerbate alcohol- and acetaminophen-induced toxicity via CYP2E1 pathway
por: Rahman, Mohammad A., et al.
Publicado: (2019)

Exacerbated Airway Toxicity of Environmental Oxidant Ozone in Mice Deficient in Nrf2
por: Cho, Hye-Youn, et al.
Publicado: (2013)

Integrated Proteomic and Transcriptomic Investigation of the Acetaminophen Toxicity in Liver Microfluidic Biochip
por: Prot, Jean Matthieu, et al.
Publicado: (2011)

Auriculatone Sulfate Effectively Protects Mice Against Acetaminophen-Induced Liver Injury
por: Lin, Liangcai, et al.
Publicado: (2019)

Severe Acetaminophen Toxicity From the Use of Oxycodone-Acetaminophen With Normal Liver Function Tests and a Completely Asymptomatic Course of Hospitalization
por: Haider, Muhammad Adnan, et al.
Publicado: (2023)

Comparison of Bile Acids and Acetaminophen Protein Adducts in Children and Adolescents with Acetaminophen Toxicity
por: James, Laura, et al.
Publicado: (2015)

Acetaminophen toxicity: suicidal vs accidental
por: Gyamlani, Geeta G, et al.
Publicado: (2002)

Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity
por: Zhou, Haibin, et al.
Publicado: (2021)

Hepatoprotective role of liver fatty acid binding protein in acetaminophen induced toxicity
por: Gong, Yu, et al.
Publicado: (2014)

Risk of acute exacerbation between acetaminophen and ibuprofen in children with asthma
por: Fu, Lin-Shien, et al.
Publicado: (2019)

The Protective Effect of Sonneratia apetala Fruit Extract on Acetaminophen-Induced Liver Injury in Mice
por: Liu, Jingjing, et al.
Publicado: (2019)

CD5L deficiency attenuate acetaminophen-induced liver damage in mice via regulation of JNK and ERK signaling pathway
por: Li, Mengjing, et al.
Publicado: (2021)

Second exposure to acetaminophen overdose is associated with liver fibrosis in mice
por: AlWahsh, Mohammad, et al.
Publicado: (2019)

Immature mice are more susceptible than adult mice to acetaminophen-induced acute liver injury
por: Lu, Yan, et al.
Publicado: (2017)

Serotonin and YAP/VGLL4 Balance Correlated with Progression and Poor Prognosis of Hepatocellular Carcinoma
por: Shu, Bo, et al.
Publicado: (2018)

Effects of food restriction on the expression of genes related to acetaminophen-induced liver toxicity in rats
por: Tsuchiya, Yuya, et al.
Publicado: (2018)

Mitigation of acetaminophen-induced liver toxicity by the novel phosphatidylinositol 3-kinase inhibitor alpelisib
por: Shaker, Mohamed E., et al.
Publicado: (2023)

Acetaminophen Toxicity: When to Consult the Transplant Surgeon
por: Sebastian, Raynard J., et al.
Publicado: (2000)

Hepatoprotective Effect of Polyphenol-Enriched Fraction from Folium Microcos on Oxidative Stress and Apoptosis in Acetaminophen-Induced Liver Injury in Mice
por: Wu, Hongtan, et al.
Publicado: (2017)

Comparison of toxic responses to acetaminophen challenge in ICR mice originating from different sources
por: Jeong, Tae Bin, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_l23cvqth0p2u3794pileif9bsk