Effects of L-type calcium channel and human ether-a-go-go related gene blockers on the electrical activity of the human heart: a simulation study

AIMS: Class III and IV drugs affect cardiac human ether-a-go-go related gene (I(Kr)) and L-type calcium (I(CaL)) channels, resulting in complex alterations in repolarization with both anti- and pro-arrhythmic consequences. Interpretation of their effects on cellular and electrocardiogram (ECG)-based...

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Detalles Bibliográficos
Autores principales: Zemzemi, Nejib, Rodriguez, Blanca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309991/
https://www.ncbi.nlm.nih.gov/pubmed/25228500
http://dx.doi.org/10.1093/europace/euu122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309991/
https://www.ncbi.nlm.nih.gov/pubmed/25228500
http://dx.doi.org/10.1093/europace/euu122

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