Rational selection of experimental readout and intervention sites for reducing uncertainties in computational model predictions

BACKGROUND: Understanding the dynamics of biological processes can substantially be supported by computational models in the form of nonlinear ordinary differential equations (ODE). Typically, this model class contains many unknown parameters, which are estimated from inadequate and noisy data. Depe...

Descripción completa

Detalles Bibliográficos
Autores principales: Flassig, Robert J, Migal, Iryna, der Zalm, Esther van, Rihko-Struckmann, Liisa, Sundmacher, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310145/
https://www.ncbi.nlm.nih.gov/pubmed/25592474
http://dx.doi.org/10.1186/s12859-014-0436-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310145/
https://www.ncbi.nlm.nih.gov/pubmed/25592474
http://dx.doi.org/10.1186/s12859-014-0436-5

Ejemplares similares