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Rational selection of experimental readout and intervention sites for reducing uncertainties in computational model predictions
BACKGROUND: Understanding the dynamics of biological processes can substantially be supported by computational models in the form of nonlinear ordinary differential equations (ODE). Typically, this model class contains many unknown parameters, which are estimated from inadequate and noisy data. Depe...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310145/ https://www.ncbi.nlm.nih.gov/pubmed/25592474 http://dx.doi.org/10.1186/s12859-014-0436-5 |