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Regulation of Ca(2+) transient by PP2A in normal and failing heart

Calcium transient in cardiomyocytes is regulated by multiple protein kinases and phosphatases. PP2A is a major protein phosphatase in the heart modulating Ca(2+) handling through an array of ion channels, antiporters and pumps, etc. The assembly, localization/translocation, and substrate specificity...

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Detalles Bibliográficos
Autores principales: Lei, Ming, Wang, Xin, Ke, Yunbo, Solaro, R. John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310266/
https://www.ncbi.nlm.nih.gov/pubmed/25688213
http://dx.doi.org/10.3389/fphys.2015.00013