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Circulating Dickkopf‐1 in Diabetes Mellitus: Association With Platelet Activation and Effects of Improved Metabolic Control and Low‐Dose Aspirin

BACKGROUND: Dickkopf‐1 (DKK‐1) is a major regulator of the Wnt signaling pathway, involved in inflammation, atherogenesis, and the regulation of glucose metabolism. Because platelets are major contributors to circulating levels of DKK‐1 in other clinical settings, we aimed at characterizing the plat...

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Detalles Bibliográficos
Autores principales: Lattanzio, Stefano, Santilli, Francesca, Liani, Rossella, Vazzana, Natale, Ueland, Thor, Di Fulvio, Patrizia, Formoso, Gloria, Consoli, Agostino, Aukrust, Pål, Davì, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310390/
https://www.ncbi.nlm.nih.gov/pubmed/25037197
http://dx.doi.org/10.1161/JAHA.114.001000